Emerging therapeutics in idiopathic inflammatory myopathy
نویسندگان
چکیده
منابع مشابه
Respiratory chain enzyme defects in patients with idiopathic inflammatory myopathy.
OBJECTIVE To analyse muscle respiratory chain enzymes in idiopathic inflammatory myopathy. METHODS Four consecutive female patients seen at our hospital with idiopathic inflammatory myopathy were studied. Muscle histochemical staining included NADH tetrazolium reductase and succinate dehydrogenase tests. Activity of rotenone sensitive NADH cytochrome c reductase (complex I and III) succinate ...
متن کاملRecent advances in the immunogenetics of idiopathic inflammatory myopathy
This review summarizes the previous and current literature on the immunogenetics of idiopathic inflammatory myopathy (IIM) and updates the research progress that has been made over the past decade. A substantial part of the genetic risk for developing adult- and juvenile-onset IIM lies within the major histocompatibility complex (MHC), and a tight relationship exists between individual human le...
متن کاملQuantitative nailfold video capillaroscopy in patients with idiopathic inflammatory myopathy.
OBJECTIVES To quantify nailfold capillary density and dimensions in patients with idiopathic inflammatory myopathy (IIM) and compare them with those in healthy controls; to look for associations with microvascular disease in IIM; and to determine whether nailfold capillary density and dimensions change over time. METHODS Nailfold video microscopy (x300 magnification) was performed on 24 patie...
متن کاملCase Report: Elevated CPK, an indicator of idiopathic inflammatory myopathy?
Polymyositis is a rare disease with incidence rates at about 1 per 100,000 people annually. In this case report we will review a case of proximal muscle weakness with an elevated creatine phosphokinase that was initially misdiagnosed twice as rhabdomyolysis. Therefore, emphasizing that idiopathic inflammatory myopathy is a potential cause of myasthenia that must be considered in the differentia...
متن کاملNecrotizing Autoimmune Myopathy: A Rare Variant of Idiopathic Inflammatory Myopathies
Idiopathic inflammatory myopathies are an unusual group of myopathies with annual incidence of 1 in 100 000 people in the United States. Necrotizing autoimmune myopathy comprises only 16% of this group. It usually presents with severe proximal weakness, lower extremity weakness, and severe fatigue while very rarely does it present with dysphagia and respiratory muscle weakness. Statin use, canc...
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ژورنال
عنوان ژورنال: Indian Journal of Rheumatology
سال: 2020
ISSN: 0973-3698
DOI: 10.4103/injr.injr_124_20